SCHEMBL14280817

SCHEMBL14280817

C/C(=N\c1c(C)cc(C)cc1C)c1cc(Cl)cc(/C(C)=N/c2c(C)cc(C)cc2C)n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.33
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7176562 0.97 RAPGEF4 (0.32) RAPGEF4
Hydrochloric Acid SCHEMBL7180648 0.97 RAPGEF4 (0.32) RAPGEF4
Hydrochloric Acid SCHEMBL7174196 0.97 RAPGEF4 (0.32) RAPGEF4
Hydrochloric Acid SCHEMBL7171291 0.97 RAPGEF4 (0.32) RAPGEF4
Hydrochloric Acid SCHEMBL7176179 0.97 RAPGEF4 (0.32) RAPGEF4
Hydrochloric Acid SCHEMBL7177030 0.97 RAPGEF4 (0.32) RAPGEF4
Hydrochloric Acid SCHEMBL7184006 0.97 RAPGEF4 (0.32) RAPGEF4
SCHEMBL6912292 0.89 KDM4E (0.33)
SCHEMBL6912296 0.89 KDM4E (0.33)
Hydrochloric Acid SCHEMBL7176713 0.86 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed