Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.42 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4874621 | 0.89 | CNR1 (0.40) | CNR1CNR2AVPR2AVPR1A | |
| SCHEMBL4870438 | 0.88 | CNR1 (0.38) | CNR1CNR2AVPR2AVPR1A | |
| SCHEMBL4872141 | 0.85 | AVPR2 (0.45) | CNR1CNR2AVPR2AVPR1A | |
| SCHEMBL4867917 | 0.81 | CNR1 (0.56) | CNR1AVPR2AVPR1A | |
| SCHEMBL4867204 | 0.77 | GAA (0.44) | CNR1CNR2 | |
| SCHEMBL3551944 | 0.75 | CNR1 (0.50) | CNR1CNR2 | |
| SCHEMBL4873206 | 0.74 | CNR1 (0.48) | CNR1 | |
| SCHEMBL3551790 | 0.74 | CNR1 (0.39) | CNR1CNR2 | |
| SCHEMBL4867191 | 0.73 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL4871547 | 0.73 | CNR1 (0.56) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317012-B2 | Bicyclic heterocycles as cannabinoind-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-08 | — | — | US | disclosed |