Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687512 | 1.00 | CPS1 (0.48) | CPS1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3687434 | 0.96 | CPS1 (0.45) | CPS1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3687509 | 0.89 | ALDH1A1 (0.47) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3693000 | 0.89 | ALDH1A1 (0.47) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3688857 | 0.88 | CPS1 (0.48) | CPS1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3690191 | 0.87 | BACE1 (0.45) | CPS1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3690195 | 0.87 | BACE1 (0.45) | CPS1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3686775 | 0.87 | CPS1 (0.47) | CPS1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3686269 | 0.86 | CPS1 (0.46) | CPS1HPGDMEN1KMT2ALMNA | |
| SCHEMBL3687432 | 0.86 | ALDH1A1 (0.44) | CPS1HPGDMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027075-A1 | Quaternary Amino-Function Chalcones | LICA PHARMACEUTICALS A/S (DK) | 2008-01-31 | — | — | US | disclosed |
| US-20080027075-A1 | Quaternary Amino-Function Chalcones | LICA PHARMACEUTICALS A/S (DK) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027075-A1 | Quaternary Amino-Function Chalcones | NR2E1, BET1, NR0B1 | CPS1 2459/4885HPGD 4406/4885MEN1 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.