SCHEMBL1428182

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8372923	0.93	KCNH2 (0.67)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL4285630	0.89	KCNH2 (0.70)	KCNH2CACNA1HCYP2D6CACNA1IMEN1
	SCHEMBL4279303	0.89	KCNH2 (0.70)	KCNH2CACNA1HCYP2D6CACNA1IMEN1
	SCHEMBL4272178	0.89	CACNA1I (0.77)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL4274781	0.88	CACNA1I (0.75)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL4276387	0.87	KCNH2 (0.68)	KCNH2CACNA1HCYP2D6CACNA1IMEN1
	SCHEMBL4271203	0.87	CACNA1I (0.74)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL4276378	0.86	CACNA1I (0.72)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL4276552	0.85	CACNA1I (0.75)	KCNH2CACNA1HCYP2D6CACNA1ICACNA1G
	SCHEMBL4278165	0.85	CACNA1I (0.71)	KCNH2CACNA1HCYP2D6CACNA1IMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.