Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803896 | 0.77 | LMNA (0.44) | LMNAMAPK1HTT | |
| SCHEMBL20781186 | 0.77 | LMNA (0.44) | LMNAMAPK1HTT | |
| SCHEMBL284533 | 0.77 | — | — | |
| SCHEMBL284532 | 0.77 | — | — | |
| SCHEMBL408223 | 0.77 | — | — | |
| SCHEMBL642285 | 0.76 | LMNA (0.39) | LMNAMAPK1HTT | |
| SCHEMBL642286 | 0.76 | LMNA (0.39) | LMNAMAPK1HTT | |
| Hydrochloric Acid SCHEMBL11798083 | 0.75 | — | — | |
| SCHEMBL2933003 | 0.72 | LMNA (0.37) | LMNAMAPK1HTT | |
| SCHEMBL2933002 | 0.72 | LMNA (0.37) | LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015225-A1 | Dimeric Piperidine Derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-17 | — | — | US | disclosed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015225-A1 | Dimeric Piperidine Derivatives | PTGER4, PTGER3, PTGER1 | LMNA 2600/4885MAPK1 2753/4885HTT 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.