Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282906 | 0.88 | PRCP (0.44) | — | |
| SCHEMBL4071991 | 0.80 | CHRM2 (0.59) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL14282939 | 0.79 | BACE1 (0.46) | CYP2D6 | |
| SCHEMBL4254317 | 0.78 | BCHE (0.59) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Hydrochloric Acid SCHEMBL9356588 | 0.77 | BCHE (0.58) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL14282981 | 0.76 | BCHE (0.60) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL4562834 | 0.76 | CHRM2 (0.57) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL14198372 | 0.75 | CHRM2 (0.61) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL6250832 | 0.75 | BCHE (0.63) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL14559344 | 0.74 | BCHE (0.57) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |