Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282906 | 0.91 | PRCP (0.44) | BACE1NPY2RPRCP | |
| SCHEMBL14282923 | 0.80 | OPRD1 (0.41) | — | |
| SCHEMBL14282903 | 0.79 | CHRM2 (0.47) | CYP2D6 | |
| SCHEMBL14282927 | 0.74 | BACE1 (0.52) | BACE1NPY2RTSHR | |
| SCHEMBL14282925 | 0.71 | OPRD1 (0.45) | — | |
| SCHEMBL3662230 | 0.71 | BACE1 (0.58) | BACE1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4253158 | 0.71 | PRCP (0.55) | BACE1NPY2RPRCP | |
| SCHEMBL4695183 | 0.69 | PRCP (0.52) | BACE1PRCPCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14198386 | 0.68 | BACE1 (0.50) | BACE1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL14282940 | 0.68 | ALDH1A1 (0.52) | NPY2RPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |