Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563119 | 0.86 | OPRD1 (0.54) | OPRD1OPRK1OPRM1SETD7MEN1 | |
| SCHEMBL11037050 | 0.82 | OPRD1 (0.53) | OPRD1OPRK1OPRM1SETD7MEN1 | |
| SCHEMBL4693977 | 0.81 | TSHR (0.57) | OPRD1OPRK1SETD7KMT2AKDM4E | |
| SCHEMBL4257154 | 0.81 | SETD7 (0.56) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL11033476 | 0.80 | OPRD1 (0.51) | OPRD1OPRK1OPRM1SETD7MEN1 | |
| SCHEMBL3067438 | 0.79 | BLM (0.57) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16481505 | 0.79 | OPRD1 (0.54) | OPRD1OPRK1OPRM1KDM4EHTR7 | |
| SCHEMBL11036336 | 0.78 | SETD7 (0.53) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| Carbamic Acid SCHEMBL4082824 | 0.78 | TSHR (0.53) | OPRD1OPRK1SETD7KMT2AKDM4E | |
| SCHEMBL14198385 | 0.77 | SETD7 (0.65) | OPRD1OPRK1OPRM1SETD7HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |