Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198340 | 0.91 | SETD7 (0.57) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| SCHEMBL11545924 | 0.90 | DRD2 (0.64) | OPRD1OPRM1OPRK1P2RX7HTR7 | |
| Hydrochloric Acid SCHEMBL11543149 | 0.88 | DRD2 (0.63) | OPRD1OPRM1OPRK1P2RX7HTR7 | |
| SCHEMBL13904313 | 0.83 | DRD2 (0.65) | OPRM1HTR7DRD2HTR1AHTR2A | |
| SCHEMBL11541244 | 0.83 | DRD2 (0.65) | OPRM1HTR7DRD2HTR1AHTR2A | |
| SCHEMBL14198374 | 0.82 | SETD7 (0.58) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| Hydrochloric Acid SCHEMBL11545929 | 0.82 | DRD2 (0.63) | OPRM1HTR7DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL11547031 | 0.82 | CYP2J2 (0.57) | OPRD1OPRM1OPRK1HTR7DRD2 | |
| SCHEMBL9249824 | 0.81 | SETD7 (0.57) | OPRD1OPRM1OPRK1P2RX7SETD7 | |
| SCHEMBL9253379 | 0.81 | SETD7 (0.57) | OPRD1OPRM1OPRK1P2RX7SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189757-B2 | Treatment of sleep disorders using CNS target modulators | HYPNION, INC. (US) | 2007-03-13 | — | — | US | disclosed |