Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.51 |
| ▸ | PGR | P06401 | 6/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.51 |
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308729 | 0.86 | HIF1A (0.54) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14285044 | 0.81 | HIF1A (0.66) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14568530 | 0.81 | HIF1A (0.66) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14508986 | 0.79 | NR3C1 (0.70) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14565704 | 0.79 | NR3C1 (0.70) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14450055 | 0.79 | NR3C1 (0.70) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14567743 | 0.79 | NR3C1 (0.70) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14084961 | 0.79 | NR3C1 (0.70) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL31277081 | 0.79 | NR3C1 (0.70) | HIF1ALMNANR3C2PGRNR3C1 | |
| SCHEMBL14567820 | 0.79 | NR3C1 (0.70) | HIF1ALMNANR3C2PGRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027237-A1 | Processes for preparations of 9,11-epoxy steroids and intermediates useful therein | NG JOHN S | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027237-A1 | Processes for preparations of 9,11-epoxy steroids and intermediates useful therein | CYP4A11, CYP11B1, CYP17A1 | HIF1A 2302/4885LMNA 1449/4885NR3C2 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.