Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382267 | 1.00 | HSP90AA1 (0.62) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL5162147 | 0.84 | MEN1 (0.56) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL4050154 | 0.84 | MEN1 (0.56) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL1156333 | 0.84 | MEN1 (0.56) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL23837627 | 0.82 | MEN1 (0.55) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL14223791 | 0.82 | MEN1 (0.55) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL2700313 | 0.82 | MEN1 (0.55) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL2313381 | 0.82 | MEN1 (0.55) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL23837601 | 0.82 | MEN1 (0.55) | HSP90AA1MEN1KMT2AALPLPOLB | |
| SCHEMBL11856720 | 0.81 | AMY1A (0.56) | HSP90AA1MEN1KMT2AALPLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150192589-A1 | METHOD USING FLUORESCENT TURN-ON PROBES FOR CELL-SPECIFIC DETECTION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-07-09 | — | — | US | disclosed |
| US-20150192589-A1 | METHOD USING FLUORESCENT TURN-ON PROBES FOR CELL-SPECIFIC DETECTION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-07-09 | — | — | US | disclosed |
| US-20080015194-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph (US) | 2008-01-17 | — | — | US | disclosed |
| US-20080015194-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph (US) | 2008-01-17 | — | — | US | disclosed |
| WO-2007087266-A2 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | ERRICO JOSEPH P (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015194-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | CD74, HAVCR2, CD47 | HSP90AA1 161/4885MEN1 4461/4885KMT2A 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.