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Sugi Predict / Targets / AMY1A

AMY1A

Alpha-amylase 1A · P0DUB6 · AMY1A on Sugi Atlas →

34,801 patent compounds predicted against AMY1A, 22,772 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL419809 SCHEMBL419809 0.68 16/20
SCHEMBL420556 SCHEMBL420556 0.67 15/20
SCHEMBL420933 SCHEMBL420933 0.58 10/20
SCHEMBL424354 SCHEMBL424354 0.48 10/20
SCHEMBL418912 SCHEMBL418912 0.76 9/20
SCHEMBL170673 SCHEMBL170673 0.71 9/20
SCHEMBL425007 SCHEMBL425007 0.58 9/20
SCHEMBL425552 SCHEMBL425552 0.56 9/20
SCHEMBL202954 SCHEMBL202954 0.54 9/20
SCHEMBL419818 SCHEMBL419818 0.52 9/20
SCHEMBL424622 SCHEMBL424622 0.48 9/20
SCHEMBL425440 SCHEMBL425440 0.48 9/20
SCHEMBL108928 SCHEMBL108928 0.64 8/20
SCHEMBL108929 SCHEMBL108929 0.64 8/20
SCHEMBL218723 SCHEMBL218723 0.59 8/20
SCHEMBL425444 SCHEMBL425444 0.56 8/20
SCHEMBL361654 SCHEMBL361654 0.73 7/20
SCHEMBL419548 SCHEMBL419548 0.60 7/20
SCHEMBL419547 SCHEMBL419547 0.56 7/20
SCHEMBL419812 SCHEMBL419812 0.50 7/20

Clinical trials — most relevant to AMY1A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Confirmatory Clinical Study in NSCLC Patients With MET Exon 14 Mutation (KUNPENG-2) PHASE3RECRUITING
A Double-Blind, Placebo-Controlled Study of Fermented Deglycyrrhizinated Licorice Extract PHASE2COMPLETED
Effect of Moringa Leaf Capsules on Glycemic Control of Type 2 Diabetic Patients PHASE2UNKNOWN
Perioperative Salivary Alpha-amylase as a Predictor of Delirium After Lower Extremity Vascular Bypass Surgery nanCOMPLETED
Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress Marker nanCOMPLETED
Acute Pancreatitis Targets (APT) Study nanCOMPLETED
Effects of Seaweed Extract on Postprandial Response to White Bread nanUNKNOWN
The Role of Salivary Alpha Amylase in Sepsis nanCOMPLETED
Clinical and Economic Validation of the ISGPS Definition of PPAP nanCOMPLETED
Tracheal Dosage of Amylase : a New Surrogate for Microaspirations in Ventilated ICU Patients nanCOMPLETED
Effect of Proprietary Botanical Blend on Glycemic Control and Post-prandial Carbohydrate Absorption nanUNKNOWN
Extra Virgin Olive Oil on Glycemic Control ,Insulin Resistance and Insulin Secretion nanUNKNOWN
Markers in Acute Pancreatitis-1 nanCOMPLETED
Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-induced Xerostomia in Comparison With the Hygiene Rules nanUNKNOWN
Music Therapy in Restorative Dentistry nanRECRUITING
Psychiatric Symptoms in Employees Experiencing High Levels of Stress Before and After the Intake of Probiotics nanCOMPLETED
Translation and Validation of Chinese COMPAT-SF nanRECRUITING
Emotions From Salivary Biomarkers in an Architectural Context nanNOT_YET_RECRUITING
Early Drain Removal Versus Standard Drain Management After Distal Pancreatectomy (Early-Dist) nanCOMPLETED
Indian Ragas on Health - a Electrophysiological Study (RAGA-1) nanCOMPLETED
Select Indian Ragas on Electrophysiological Parameters nanCOMPLETED
Effect of General and Non-general Anesthesia on Perioperative Depression or Anxiety nanCOMPLETED
A Pilot Study of Biomarkers of Stress in Youth Who Use Teens.Connect nanCOMPLETED
EUS-guided FNB-induced PANCREatitis Assessment nanRECRUITING
Allopurinol in Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis nanCOMPLETED
Feasibility and Effectiveness of Three-day Discharge After Distal Pancreatectomy nanNOT_YET_RECRUITING
Management of Traumatic Pancreas Transection nanRECRUITING
Early Oral Refeeding in Mild Acute Pancreatitis nanCOMPLETED
Pancreatic Exocrine Insufficiency in Acute Pancreatitis nanCOMPLETED
Integrative Group Psychotherapy (Terebenin's Method) in Adults With Subclinical and Mild/Moderate Anxiety and Depression nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a AMY1A binder may also engage these)

ProteinNameSimilarity
P0DTE7 — 1.000 P0DTE7 →
P19961 — 1.000 P19961 →
AMY2A Pancreatic alpha-amylase 1.000 landscape →
P0DTE8 — 1.000 P0DTE8 →
P00689 — 0.998 P00689 →
P00687 — 0.995 P00687 →
P00688 — 0.993 P00688 →
P00690 — 0.991 P00690 →
P83053 — 0.989 P83053 →
H2N0D4 — 0.983 H2N0D4 →
P54215 — 0.970 P54215 →
P08144 — 0.970 P08144 →
Q23835 — 0.968 Q23835 →
O18345 — 0.967 O18345 →
P27937 — 0.967 P27937 →
Q9BN01 — 0.966 Q9BN01 →
P17859 — 0.966 P17859 →
P27939 — 0.964 P27939 →
P83833 — 0.964 P83833 →
P81641 — 0.964 P81641 →
P09107 — 0.963 P09107 →
P04063 — 0.962 P04063 →
P04747 — 0.959 P04747 →
P27934 — 0.959 P27934 →
P56634 — 0.959 P56634 →
O18552 — 0.957 O18552 →
P91778 — 0.956 P91778 →
O77011 — 0.955 O77011 →
O18408 — 0.955 O18408 →
O77016 — 0.954 O77016 →