Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602145 | 1.00 | TGFBR1 (0.39) | TGFBR1GAASMN1; SMN2TSHRCA1 | |
| SCHEMBL4330718 | 0.81 | CNR1 (0.36) | TGFBR1TSHRCA1CA2CA7 | |
| SCHEMBL12282666 | 0.80 | CA1 (0.42) | SMN1; SMN2TSHRCA1CA2CA7 | |
| SCHEMBL14285963 | 0.78 | TGFBR1 (0.37) | TGFBR1GAASMN1; SMN2TSHRCA1 | |
| SCHEMBL13815217 | 0.74 | GAA (0.44) | TGFBR1GAASMN1; SMN2TSHRCA1 | |
| SCHEMBL9557062 | 0.71 | CA1 (0.44) | TGFBR1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL903800 | 0.71 | CA1 (0.44) | TGFBR1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL1261511 | 0.70 | CNR1 (0.39) | TGFBR1TSHRCA1CA2CA7 | |
| SCHEMBL14350678 | 0.70 | MAPT (0.42) | TGFBR1SMN1; SMN2CA1CA2CA7 | |
| SCHEMBL1120240 | 0.70 | CNR1 (0.39) | TGFBR1TSHRCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658298-B1 | PHOSPHORUS-CONTAINING IMIDAZOLINES AND METAL COMPLEXES THEREOF | SOLVIAS AG (CH) | 2008-03-26 | — | — | EP | disclosed |