Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545575 | 0.85 | — | — | |
| SCHEMBL4378460 | 0.82 | GPR84 (0.44) | GPR84ALDH1A1MAPK1FFAR4FFAR1 | |
| SCHEMBL14533070 | 0.82 | GPR84 (0.44) | GPR84ALDH1A1MAPK1FFAR4FFAR1 | |
| SCHEMBL14533072 | 0.82 | GPR84 (0.44) | GPR84ALDH1A1MAPK1FFAR4FFAR1 | |
| SCHEMBL31509349 | 0.80 | GPR84 (0.40) | OPRM1SPHK1GPR84ALDH1A1FFAR4 | |
| SCHEMBL109319 | 0.80 | GPR84 (0.40) | OPRM1SPHK1GPR84ALDH1A1FFAR4 | |
| SCHEMBL428260 | 0.80 | GPR84 (0.40) | SPHK1GPR84ALDH1A1TSHRMAPT | |
| SCHEMBL31509354 | 0.80 | GPR84 (0.40) | OPRM1SPHK1GPR84ALDH1A1FFAR4 | |
| SCHEMBL25330209 | 0.79 | FFAR4 (0.39) | OPRM1SPHK1TP53SLC1A3SLC1A2 | |
| SCHEMBL9235843 | 0.78 | GPR84 (0.39) | OPRM1SPHK1GPR84ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7318932-B2 | Coatings for drug delivery devices comprising hydrolitically stable adducts of poly(ethylene-co-vinyl alcohol) and methods for fabricating the same | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2008-01-15 | — | — | US | disclosed |