Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14286222 | 0.90 | MAPT (0.36) | MAPTLMNARXFP1TP53THRB | |
| SCHEMBL14286215 | 0.85 | MAPT (0.36) | MAPTLMNARXFP1TP53THRB | |
| SCHEMBL14286252 | 0.85 | MAPT (0.41) | MAPTLMNARXFP1TP53THRB | |
| SCHEMBL14286081 | 0.79 | MAPT (0.37) | MAPTLMNARXFP1TP53THRB | |
| SCHEMBL14286088 | 0.78 | PPARG (0.46) | — | |
| SCHEMBL14286078 | 0.77 | MAPT (0.43) | MAPTLMNARXFP1TP53THRB | |
| SCHEMBL14286115 | 0.75 | PPARG (0.49) | MAPTLMNARXFP1THRBNOTUM | |
| SCHEMBL14286068 | 0.75 | PPARA (0.58) | — | |
| SCHEMBL14224012 | 0.75 | PPARA (0.58) | — | |
| SCHEMBL14286111 | 0.75 | PPARG (0.48) | MAPTLMNARXFP1THRBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348426-B1 | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | DR. REDDY'S LABORATIES LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |