Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.50 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802981 | 0.87 | PTGIR (0.52) | PTGIRPTGDRTBXA2R | |
| SCHEMBL6802991 | 0.87 | PTGIR (0.52) | PTGIRPTGDRTBXA2R | |
| SCHEMBL14265713 | 0.87 | PTGIR (0.50) | PTGIRPTGDRTBXA2R | |
| SCHEMBL6802985 | 0.87 | PTGIR (0.52) | PTGIRPTGDRTBXA2R | |
| SCHEMBL6316993 | 0.85 | PTGIR (0.49) | PTGIRPTGDRTBXA2R | |
| SCHEMBL14286251 | 0.85 | SIRT1 (0.43) | PTGIR | |
| SCHEMBL6316987 | 0.85 | PTGIR (0.49) | PTGIRPTGDRTBXA2R | |
| SCHEMBL5107348 | 0.85 | PTGIR (0.52) | PTGIRPTGDRTBXA2R | |
| SCHEMBL2189810 | 0.85 | PTGIR (0.52) | PTGIRPTGDRTBXA2R | |
| SCHEMBL2189965 | 0.77 | PTGIR (0.64) | PTGIRPTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348426-B1 | Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents | DR. REDDY'S LABORATIES LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |