Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.68 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.60 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14287660 | 1.00 | HRH3 (0.68) | HRH3ACHERAD52KMT2ACACNA1B | |
| SCHEMBL5107405 | 0.96 | HRH3 (0.64) | HRH3ACHERAD52KMT2A | |
| SCHEMBL14287674 | 0.94 | HRH3 (0.68) | HRH3ACHERAD52CACNA1BCACNA1H | |
| SCHEMBL5097548 | 0.92 | HRH3 (0.71) | HRH3ACHERAD52KMT2A | |
| Hydrochloric Acid SCHEMBL5100664 | 0.91 | HRH3 (0.70) | HRH3ACHERAD52KMT2A | |
| SCHEMBL14287677 | 0.89 | HRH3 (0.66) | HRH3ACHERAD52 | |
| SCHEMBL14287710 | 0.88 | HRH3 (0.70) | HRH3ACHERAD52 | |
| SCHEMBL5100294 | 0.88 | KMT2A (0.59) | HRH3ACHERAD52KMT2A | |
| SCHEMBL14287672 | 0.87 | HRH3 (0.71) | HRH3ACHERAD52 | |
| SCHEMBL14287670 | 0.86 | HRH3 (0.70) | HRH3ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |