Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14287830 | 0.81 | HRH3 (0.77) | HRH3TSHRCHRM2 | |
| SCHEMBL3581584 | 0.80 | HRH3 (1.00) | HRH3TSHR | |
| SCHEMBL14287702 | 0.79 | HRH3 (0.78) | HRH3TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL14287706 | 0.79 | HRH3 (0.76) | HRH3 | |
| SCHEMBL14287714 | 0.76 | HRH3 (0.81) | HRH3TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL14287704 | 0.75 | HRH3 (0.79) | HRH3TSHRNPC1RAB9ATP53 | |
| SCHEMBL3576962 | 0.74 | HRH3 (1.00) | HRH3TSHRCHRM2 | |
| SCHEMBL14872735 | 0.72 | TSHR (0.72) | HRH3TSHRCHRM2NPC1RAB9A | |
| SCHEMBL14287667 | 0.72 | SCN9A (0.48) | HRH3 | |
| SCHEMBL15963172 | 0.72 | LTA4H (0.53) | HRH3CHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |