Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN4 | P29074 | 2/20 | 0.42 |
| ▸ | PTPN9 | P43378 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340142 | 0.88 | CFTR (0.69) | CFTRALDH1A1CA2CA4CA5A | |
| SCHEMBL806049 | 0.86 | CFTR (1.00) | CFTRALDH1A1CA2CA4CA5A | |
| SCHEMBL14287997 | 0.82 | CFTR (0.82) | CFTRALDH1A1CA2CA4CA5A | |
| SCHEMBL28123560 | 0.82 | CFTR (0.67) | CFTRALDH1A1CA2CA4CA5A | |
| SCHEMBL5668125 | 0.82 | CFTR (0.67) | CFTRALDH1A1CA2CA4CA5A | |
| SCHEMBL752882 | 0.80 | CFTR (0.78) | CFTRALDH1A1CA2CA4CA5A | |
| Phosphine SCHEMBL28019640 | 0.80 | CFTR (0.64) | CFTRALDH1A1CA2CA4CA5A | |
| SCHEMBL171269 | 0.80 | CFTR (0.78) | CFTRALDH1A1CA2CA4CA5A | |
| Phosphine SCHEMBL27883782 | 0.78 | CFTR (0.75) | CFTRALDH1A1CA2CA4CA5A | |
| SCHEMBL14809684 | 0.78 | CFTR (0.75) | CFTRALDH1A1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017647-A1 | A MOLD WITH A METALLIC SURFACE TO WHICH A PRETREATMENT LAYER HAS BEEN APPLIED, COMPRISING A PHOSPHINIC ACID DERIVATIVE | BASF SE (DE) | 2008-02-14 | — | — | WO | disclosed |
| EP-1887022-A1 | Substrates having metalic surface and pretreatment layer containing a phosphinic acid derivate applied thereon | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-13 | — | — | EP | disclosed |