Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 17/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 17/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 15/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823023 | 0.85 | CHRM2 (0.62) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6882714 | 0.79 | ALDH1A1 (0.79) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL30433983 | 0.79 | ALDH1A1 (0.79) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL18688684 | 0.79 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL5668195 | 0.78 | ALDH1A1 (0.77) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL28638610 | 0.78 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL29930240 | 0.78 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL21248553 | 0.77 | CHRM2 (0.65) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL10559940 | 0.77 | ALDH1A1 (0.58) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL25277467 | 0.76 | ALDH1A1 (0.74) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |