Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14289220 | 0.93 | EDNRB (0.68) | EDNRBEDNRA | |
| SCHEMBL5501326 | 0.89 | EDNRB (0.89) | EDNRBEDNRA | |
| SCHEMBL14289232 | 0.88 | EDNRB (0.71) | EDNRBEDNRA | |
| SCHEMBL5494210 | 0.82 | EDNRA (1.00) | EDNRBEDNRA | |
| SCHEMBL5497129 | 0.81 | EDNRB (0.76) | EDNRBEDNRA | |
| SCHEMBL8801730 | 0.81 | EDNRB (0.81) | EDNRBEDNRA | |
| SCHEMBL8657549 | 0.81 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL14289221 | 0.81 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL5497920 | 0.80 | EDNRA (0.87) | EDNRBEDNRA | |
| SCHEMBL14380530 | 0.79 | EDNRA (1.00) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323465-B2 | Alkansulfonamides as endothelin antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-01-29 | — | — | US | disclosed |
| US-7323465-B2 | Alkansulfonamides as endothelin antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2008-01-29 | — | — | US | disclosed |