Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MIF | P14174 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241901 | 0.91 | MAPT (0.74) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL23241902 | 0.91 | MAPT (0.74) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL6423387 | 0.84 | MAPT (0.76) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL3266677 | 0.84 | MAPT (0.76) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL12979794 | 0.84 | MAPT (0.76) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL5767618 | 0.84 | MAPT (0.71) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL1573369 | 0.84 | KDM4E (0.67) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL1573371 | 0.84 | KDM4E (0.67) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL13401232 | 0.82 | MIF (0.78) | RAB9AMAPTSMN1; SMN2NPC1KDM4E | |
| SCHEMBL13903541 | 0.82 | MIF (0.68) | RAB9AMAPTSMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004256-A1 | Amidinophenylalanine Derivatives as Thrombin Inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2008-01-03 | — | — | US | disclosed |
| US-7285547-B2 | Amidinophenylalanine derivatives as thrombin inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2007-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004256-A1 | Amidinophenylalanine Derivatives as Thrombin Inhibitors | TFPI, SERPINC1, F2 | RAB9A 1859/4885MAPT 2136/4885SMN1; SMN2 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.