Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718990 | 0.88 | FAAH (0.59) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| SCHEMBL2428624 | 0.86 | MAPT (0.56) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| SCHEMBL4693223 | 0.85 | PPARG (0.55) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| SCHEMBL4682703 | 0.82 | MAPT (0.79) | MAPTPOLBSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4679879 | 0.82 | MAPT (0.53) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| SCHEMBL2423765 | 0.82 | FAAH (0.59) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| SCHEMBL4682118 | 0.81 | MAPT (0.47) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| SCHEMBL2423857 | 0.79 | MAPT (0.48) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| SCHEMBL14215640 | 0.77 | MAPT (0.48) | MAPTPOLBSMN1; SMN2TDP1FAAH | |
| Hydrochloric Acid SCHEMBL4717037 | 0.77 | MAPT (0.47) | MAPTPOLBSMN1; SMN2TDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |