Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CPN1 | P15169 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10305143 | 1.00 | ALDH1A1 (0.53) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL6290056 | 0.89 | ALDH1A1 (0.69) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL8284598 | 0.88 | ALDH1A1 (0.64) | ALDH1A1LMNANPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1692191 | 0.86 | ALDH1A1 (0.62) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL13189049 | 0.85 | NPC1 (0.56) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL17740063 | 0.85 | NPC1 (0.56) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL17815867 | 0.83 | — | — | |
| SCHEMBL24456999 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL16621832 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL13727214 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889845-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SmithKline Beecham P.L.C. (GB) | 2008-02-20 | — | — | EP | disclosed |