Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14285021 | 0.92 | ADORA1 (0.44) | ADORA2AMAPK14ADORA1PIM1MEN1 | |
| SCHEMBL11937168 | 0.92 | ADORA1 (0.44) | ADORA2AMAPK14ADORA1PIM1MEN1 | |
| SCHEMBL11937160 | 0.88 | ADORA1 (0.46) | ADORA2AADORA1PIM1MEN1KMT2A | |
| SCHEMBL14290427 | 0.86 | ADORA1 (0.41) | ADORA2AADORA1PIM1MEN1KMT2A | |
| SCHEMBL11937159 | 0.85 | ADORA1 (0.61) | ADORA2AADORA1PIM1MEN1KMT2A | |
| SCHEMBL11937162 | 0.84 | L3MBTL1 (0.41) | ADORA2AADORA1PIM1MEN1KMT2A | |
| SCHEMBL14290444 | 0.83 | ADORA1 (0.48) | ADORA2AADORA1PIM1MEN1KMT2A | |
| SCHEMBL11937164 | 0.83 | KDM4E (0.58) | ADORA2AADORA1PIM1MEN1KMT2A | |
| SCHEMBL11937155 | 0.82 | ADORA1 (0.44) | ADORA2AADORA1PIM1MEN1KMT2A | |
| SCHEMBL3061882 | 0.82 | ADORA1 (0.44) | ADORA2AADORA1PIM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016738-A2 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | WO | disclosed |