Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937157 | 0.90 | ADORA1 (0.47) | KMT2AMEN1MAPTSMN1; SMN2ADORA1 | |
| SCHEMBL3061882 | 0.87 | ADORA1 (0.44) | KMT2AMEN1ADORA1KDM4EPIM1 | |
| SCHEMBL14290491 | 0.82 | ADORA1 (0.56) | KMT2AMEN1MAPTSMN1; SMN2ADORA1 | |
| SCHEMBL3043455 | 0.81 | KMT2A (0.51) | KMT2AMEN1MAPTADORA1KDM4E | |
| SCHEMBL3064505 | 0.81 | ADORA1 (0.48) | KMT2AMEN1MAPTADORA1KDM4E | |
| SCHEMBL11937167 | 0.79 | ADORA1 (0.46) | KMT2AMEN1MAPTADORA1KDM4E | |
| SCHEMBL11937161 | 0.79 | KMT2A (0.51) | KMT2AMEN1MAPTADORA1KDM4E | |
| SCHEMBL11937155 | 0.77 | ADORA1 (0.44) | KMT2AMEN1MAPTADORA1KDM4E | |
| SCHEMBL1678198 | 0.76 | KDM4E (0.51) | KMT2AMEN1MAPTKDM4EHPGD | |
| SCHEMBL3369385 | 0.74 | ADORA1 (0.78) | KMT2AMEN1ADORA1KDM4EPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016738-A2 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | WO | disclosed |