Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11937161 | 0.90 | KMT2A (0.51) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL14290444 | 0.89 | ADORA1 (0.48) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL3064505 | 0.85 | ADORA1 (0.48) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL11937157 | 0.81 | ADORA1 (0.47) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL14290492 | 0.81 | KMT2A (0.48) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL14290491 | 0.81 | ADORA1 (0.56) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL11937167 | 0.81 | ADORA1 (0.46) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL11937156 | 0.80 | L3MBTL1 (0.43) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL11937158 | 0.79 | ADORA1 (0.64) | KMT2AMEN1BLMADORA1ADORA2A | |
| SCHEMBL14290427 | 0.77 | ADORA1 (0.41) | KMT2AMEN1ADORA1ADORA2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618327-B2 | Antibacterial agents and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-11-01 | — | — | US | disclosed |
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-11-01 | — | — | US | disclosed |
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-11-01 | — | — | US | disclosed |
| US-8227616-B2 | Cyanopyridine antibacterial agents and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-8227616-B2 | Cyanopyridine antibacterial agents and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-8227616-B2 | Cyanopyridine antibacterial agents and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-10-14 | — | — | US | disclosed |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-10-14 | — | — | US | disclosed |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-10-14 | — | — | US | disclosed |
| US-7737164-B2 | Cyanopyridine antibacterial agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-15 | — | — | US | disclosed |
| US-7737164-B2 | Cyanopyridine antibacterial agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-15 | — | — | US | disclosed |
| US-7737164-B2 | Cyanopyridine antibacterial agents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-06-15 | — | — | US | disclosed |
| WO-2008016738-A2 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016738-A2 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-02-07 | — | — | WO | disclosed |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-01-10 | — | — | US | disclosed |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-01-10 | — | — | US | disclosed |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277252-A1 | Antibacterial Agents and Methods of Use Thereof | FDPS, ABCG2, DUT | KMT2A 4034/4885MEN1 3582/4885BLM 1044/4885 |
| US-20080009528-A1 | ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS | PCNA, ABCG2, API5 | KMT2A 3806/4885MEN1 3709/4885BLM 1020/4885 |
| US-20100261763-A1 | ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF | FDPS, CYP3A5, ABCG2 | KMT2A 3947/4885MEN1 3578/4885BLM 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.