Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291194 | 0.91 | AKR1B1 (0.40) | AKR1B1MAOBPOLBMAPK1OPRD1 | |
| SCHEMBL13003578 | 0.90 | KCNH2 (0.38) | MAOBTP53MEN1KMT2A | |
| SCHEMBL3293230 | 0.83 | AKR1B1 (0.35) | AKR1B1MAOBPOLBMAPK1OPRD1 | |
| SCHEMBL13293957 | 0.80 | KCNH2 (0.40) | TP53MEN1KMT2AMAPT | |
| SCHEMBL13003571 | 0.79 | KMT2A (0.40) | POLBKEAP1MEN1KMT2AMAPT | |
| SCHEMBL12749672 | 0.79 | AKR1B1 (0.41) | AKR1B1KEAP1MEN1RECQLKMT2A | |
| SCHEMBL3293164 | 0.79 | MEN1 (0.37) | MEN1KMT2ATSHR | |
| SCHEMBL13309981 | 0.78 | TGM2 (0.40) | MAOBMEN1KMT2A | |
| SCHEMBL12749471 | 0.74 | MEN1 (0.36) | AKR1B1POLBMEN1RECQLKMT2A | |
| SCHEMBL4296152 | 0.74 | AKR1B1 (0.61) | AKR1B1KEAP1MEN1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334320-B2 | Methods for chelation therapy | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2012-12-18 | — | — | US | disclosed |