Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.69 |
| ▸ | CA2 | P00918 | 13/20 | 0.69 |
| ▸ | CA9 | Q16790 | 13/20 | 0.69 |
| ▸ | CA12 | O43570 | 9/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19818214 | 0.89 | CA1 (0.64) | CA1CA2CA9CA12CA14 | |
| SCHEMBL19818215 | 0.87 | CA1 (0.63) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12418856 | 0.86 | CA9 (0.60) | CA1CA2CA9CA12CA14 | |
| SCHEMBL15493524 | 0.85 | P2RY6 (0.71) | CA1CA2CA9CA12CA14 | |
| SCHEMBL13045848 | 0.84 | CA1 (0.60) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12716296 | 0.81 | P2RY6 (0.62) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12307301 | 0.81 | MEN1 (0.64) | CA1CA2CA9CA12CA14 | |
| SCHEMBL10293759 | 0.81 | P2RY6 (0.64) | CA1CA2CA9CA12CA14 | |
| SCHEMBL14013405 | 0.80 | MEN1 (0.62) | CA1CA2CA9CA12CA14 | |
| Tetramethylrhodamine SCHEMBL2054818 | 0.80 | MEN1 (0.71) | CA1CA2CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022355-A2 | METHODS AND REAGENTS FOR DETECTING PHOSPHOMONOESTER GROUPS | PERKINELMER LAS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |