Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19917508 | 0.87 | ALDH1A1 (0.47) | RAB9AKMT2AMAPTSTAT1NPSR1 | |
| SCHEMBL10024348 | 0.85 | PPARG (0.37) | RAB9AKMT2AMEN1HTTGFER | |
| SCHEMBL14291430 | 0.79 | PPARG (0.36) | POLBLMNAFFAR1FFAR4 | |
| SCHEMBL19917466 | 0.74 | ALDH1A1 (0.47) | RAB9AKMT2AMEN1HTTGFER | |
| SCHEMBL19912227 | 0.72 | ALDH1A1 (0.45) | RAB9AKMT2AMEN1HTTGFER | |
| SCHEMBL13408005 | 0.72 | PPARG (0.42) | RAB9AKMT2AMEN1HTTGFER | |
| SCHEMBL30929673 | 0.72 | ALDH1A1 (0.55) | RAB9AKMT2AMAPTMEN1HTT | |
| SCHEMBL20830734 | 0.71 | TDP1 (0.54) | RAB9AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL22991499 | 0.71 | ALDH1A1 (0.44) | RAB9AKMT2AMAPTNPSR1MEN1 | |
| SCHEMBL19525796 | 0.70 | TDP1 (0.57) | RAB9AKMT2AMAPTSTAT1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022962-A2 | METHOD FOR PRODUCING N-PIPERIDINYL-BENZODIAZEPINES HAVING CGRP-ANTAGONISTIC PROPERTIES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |