Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501833 | 0.92 | KDM4E (0.32) | KDM4EALDH1A1HPGD | |
| SCHEMBL14292830 | 0.89 | MEN1 (0.31) | MEN1KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL14292828 | 0.87 | KDM4E (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL10265355 | 0.87 | KMT2A (0.33) | MEN1KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL10204393 | 0.85 | KMT2A (0.32) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL501684 | 0.84 | MEN1 (0.33) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL10204674 | 0.83 | XDH (0.32) | MEN1KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL10265710 | 0.82 | XDH (0.32) | MEN1KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL10204772 | 0.82 | GRIN1 (0.40) | — | |
| SCHEMBL10204378 | 0.82 | KDM4E (0.34) | MEN1KMT2ATDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008016522-A2 | HIV REVERSE TRANSCRIPTASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2008-02-07 | — | — | WO | disclosed |