Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483979 | 0.97 | ADRB2 (0.52) | ADRB2ADRB1ADRB3ACHECYP2D6 | |
| SCHEMBL1483981 | 0.97 | ADRB2 (0.52) | ADRB2ADRB1ADRB3ACHECYP2D6 | |
| SCHEMBL1483974 | 0.97 | ADRB2 (0.52) | ADRB2ADRB1ADRB3ACHECYP2D6 | |
| SCHEMBL4412877 | 0.91 | CYP3A4 (0.49) | TNKSCYP19A1ACHECYP2D6KDM4E | |
| SCHEMBL4407561 | 0.86 | CYP1A1 (0.48) | ADRB2ADRB1ADRB3CYP2D6 | |
| SCHEMBL1483644 | 0.85 | ADRB2 (0.47) | ADRB2ADRB1ADRB3ACHECYP2D6 | |
| SCHEMBL1484227 | 0.85 | ADRB2 (0.47) | ADRB2ADRB1ADRB3ACHECYP2D6 | |
| SCHEMBL1483645 | 0.85 | ADRB2 (0.47) | ADRB2ADRB1ADRB3ACHECYP2D6 | |
| SCHEMBL1484581 | 0.85 | ABCB1 (0.46) | — | |
| SCHEMBL4399919 | 0.83 | MEN1 (0.47) | TNKSCYP2D6KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018089-A1 | R-(-) / S-(+)-7-[3-N-SUBSTITUTED AMINO-2-HYDROXYPROPOXY] FLAVONES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-14 | — | — | WO | disclosed |