Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207101 | 0.94 | MAPT (0.43) | MAPTTP53LMNAHPGDNPSR1 | |
| SCHEMBL14293466 | 0.90 | MAPT (0.37) | MAPTTP53LMNATHRBALPL | |
| SCHEMBL14293170 | 0.88 | MAPT (0.37) | MAPTTP53LMNATHRBALPL | |
| SCHEMBL14293173 | 0.88 | MAPT (0.38) | MAPTTP53LMNATHRBALPL | |
| SCHEMBL14292943 | 0.88 | MAPT (0.40) | MAPTTP53THRBALPLALPI | |
| SCHEMBL14292951 | 0.88 | MAPT (0.42) | MAPTTP53THRBMEN1ALDH1A1 | |
| SCHEMBL14293174 | 0.86 | ALDH1A1 (0.39) | MAPTTP53LMNATHRBHPGD | |
| SCHEMBL14293465 | 0.86 | MAPT (0.37) | MAPTTP53LMNATHRBALPL | |
| SCHEMBL1208612 | 0.84 | ALDH1A1 (0.44) | MAPTTP53LMNAHPGDNPSR1 | |
| SCHEMBL14292928 | 0.83 | MAPT (0.43) | MAPTTP53THRBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |