Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14293513 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL14292933 | 0.91 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL14292386 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL12895489 | 0.91 | MGAM (0.40) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL1208399 | 0.90 | PTPN5 (0.47) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL14292931 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL14293514 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL14293000 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL14293190 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBHPGDMEN1 | |
| SCHEMBL14292369 | 0.89 | MAPT (0.38) | ALDH1A1MAPTPOLBHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |