Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12895477 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1RAB9AKCNA5MAPT | |
| SCHEMBL12895371 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1RAB9AKCNA5MAPT | |
| SCHEMBL14292425 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1RAB9AMAPTADORA2B | |
| SCHEMBL14292364 | 0.79 | HPGD (0.40) | RAB9AMAPTTP53CYP3A4 | |
| SCHEMBL12895275 | 0.78 | RAB9A (0.36) | KDM4EALDH1A1RAB9AKCNA5MAPT | |
| SCHEMBL14292368 | 0.78 | RAB9A (0.44) | KDM4EALDH1A1RAB9AKCNA5MAPT | |
| SCHEMBL14293248 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1RAB9AKCNA5MAPT | |
| SCHEMBL14292979 | 0.76 | HPGD (0.53) | ALDH1A1RAB9AMAPTL3MBTL1CYP3A4 | |
| SCHEMBL14293234 | 0.76 | HPGD (0.36) | KDM4EALDH1A1RAB9AMAPTTP53 | |
| SCHEMBL14292397 | 0.76 | HPGD (0.37) | RAB9AMAPTTP53L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020045-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | 4SC AG (DE) | 2008-02-21 | — | — | WO | disclosed |