SCHEMBL14294646

SCHEMBL14294646

CC(COC(C)(C)C(=O)CCC(=O)O)OC(=O)CCC(=O)O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.34
KDM5C P41229 1/20 0.34
EGLN1 Q9GZT9 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470670 0.77 EGLN1 (0.42) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL17506142 0.75 EGLN1 (0.41) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL11679497 0.75 EGLN1 (0.41) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL13967577 0.75 KDM6B (0.30) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL28014436 0.74 EGLN1 (0.39) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL3799285 0.74 EGLN1 (0.39) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL24479881 0.71 THRA (0.37) EGLN1PHF8KDM2A
SCHEMBL3031454 0.71 EGLN1 (0.37) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL247657 0.71 TSHR (0.38) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL644570 0.71 EGLN1 (0.43) KDM6BKDM5CEGLN1PHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080039931-A1 Hydrophilic shape memory insertable medical articles SURMODICS, INC. 2008-02-14 US disclosed