SCHEMBL14296148

SCHEMBL14296148

CC(CC(C)(C)C)SSC(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24399536 0.80
SCHEMBL22219861 0.80
SCHEMBL21524995 0.76
SCHEMBL22219833 0.74 ALDH1A1 (0.30)
SCHEMBL22327045 0.74 ALDH1A1 (0.30)
SCHEMBL13460352 0.72
SCHEMBL22219926 0.70
SCHEMBL18078574 0.69 TSHR (0.32)
SCHEMBL14296208 0.67
SCHEMBL16710831 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943609-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2018-04-17 US disclosed
US-9872918-B2 Hydroxyl-polymer-drug-protein conjugates MERSANA THERAPEUTICS, INC. (US) 2018-01-23 US disclosed
US-20170348424-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2017-12-07 US disclosed
US-9770519-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2017-09-26 US disclosed
US-20170119896-A1 TERMINALLY MODIFIED POLYMERS AND CONJUGATES THEREOF MERSANA THERAPEUTICS, INC. 2017-05-04 US disclosed
US-20160220696-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2016-08-04 US disclosed
US-20160067353-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2016-03-10 US disclosed
US-9254339-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2016-02-09 US disclosed
US-20160022829-A1 TUBULYSIN COMPOUNDS AND CONJUGATES THEREOF MERSANA THERAPEUTICS, INC. 2016-01-28 US disclosed
US-20150314008-A1 AURISTATIN COMPOUNDS AND CONJUGATES THEREOF MERSANA THERAPEUTICS, INC. 2015-11-05 US disclosed
US-20150064130-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2015-03-05 US disclosed
US-20150044160-A1 PROTEIN-POLYMER-DRUG CONJUGATES MERSANA THERAPEUTICS, INC. 2015-02-12 US disclosed
US-8821850-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2014-09-02 US disclosed
US-8815226-B2 Protein-polymer-drug conjugates MERSANA THERAPEUTICS, INC. (US) 2014-08-26 US disclosed
US-8808679-B2 Auristatin compounds and conjugates thereof MERSANA THERAPEUTICS, INC. (US) 2014-08-19 US disclosed
US-20140134127-A1 Protein-Polymer-Drug Conjugates MERSANA THERAPEUTICS, INC. (US) 2014-05-15 US disclosed
US-20140017265-A1 Terminally Modified Polymers and Conjugates Thereof MERSANA THERAPEUTICS, INC. 2014-01-16 US disclosed
US-20130309192-A1 Auristatin Compounds and Conjugates Thereof MERSANA THERAPEUTICS, INC. (US) 2013-11-21 US disclosed
US-20130101546-A1 Protein-Polymer-Drug Conjugates MERSANA THERAPEUTICS, INC. (US) 2013-04-25 US disclosed
US-20120321583-A1 Protein-Polymer-Drug Conjugates MERSANA THERAPEUTICS, INC. (US) 2012-12-20 US disclosed