Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170550 | 1.00 | BACE1 (0.62) | BACE1ALOX5 | |
| SCHEMBL1170384 | 1.00 | BACE1 (0.62) | BACE1ALOX5 | |
| SCHEMBL1170554 | 0.88 | BACE1 (0.48) | BACE1 | |
| SCHEMBL7716203 | 0.83 | BACE1 (0.43) | BACE1ALOX5 | |
| SCHEMBL14685963 | 0.83 | BACE1 (0.43) | BACE1ALOX5 | |
| SCHEMBL1170881 | 0.81 | BACE1 (0.58) | BACE1ALOX5 | |
| SCHEMBL16494479 | 0.79 | BACE1 (0.69) | BACE1 | |
| SCHEMBL4318021 | 0.79 | BACE1 (0.69) | BACE1 | |
| SCHEMBL4307297 | 0.79 | BACE1 (0.69) | BACE1 | |
| SCHEMBL1171152 | 0.77 | BACE1 (1.00) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300484-A1 | NOVEL CLASS OF SPIRO PIPERIDINES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | Pfizer Inc. (US) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009136350-A1 | NOVEL CLASS OF SPIRO PIPERIDINES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | PFIZER INC. (US) | 2009-11-12 | — | — | WO | disclosed |