Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685963 | 1.00 | BACE1 (0.43) | BACE1ALOX5 | |
| SCHEMBL1170550 | 0.83 | BACE1 (0.62) | BACE1ALOX5 | |
| SCHEMBL1170384 | 0.83 | BACE1 (0.62) | BACE1ALOX5 | |
| SCHEMBL1429675 | 0.83 | BACE1 (0.62) | BACE1ALOX5 | |
| SCHEMBL1170881 | 0.82 | BACE1 (0.58) | BACE1ALOX5 | |
| SCHEMBL7714571 | 0.77 | BACE1 (0.41) | BACE1ALOX5 | |
| SCHEMBL14685965 | 0.77 | BACE1 (0.41) | BACE1ALOX5 | |
| SCHEMBL14685981 | 0.76 | ALOX5 (0.40) | BACE1ALOX5 | |
| SCHEMBL7714109 | 0.76 | ALOX5 (0.40) | BACE1ALOX5 | |
| SCHEMBL2433644 | 0.75 | ALOX5 (0.43) | BACE1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150376-A1 | Novel Sultam Compounds | PFIZER INC. (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011125006-A2 | NOVEL SULTAM COMPOUNDS | PFIZER INC. (US) | 2011-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150376-A1 | Novel Sultam Compounds | SULT2A1, SULT1A1, SULT1E1 | BACE1 2145/4885ALOX5 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.