Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14296740 | 0.96 | ATM (0.36) | ATMKDM4EL3MBTL1HDAC4FAAH | |
| SCHEMBL14296784 | 0.95 | HDAC4 (0.35) | ATMKDM4EL3MBTL1HDAC4FAAH | |
| SCHEMBL14296755 | 0.95 | HDAC4 (0.35) | ATMKDM4EL3MBTL1HDAC4FAAH | |
| SCHEMBL14296739 | 0.93 | KDM4E (0.33) | ATMKDM4EL3MBTL1HDAC4FAAH | |
| SCHEMBL13231642 | 0.92 | KDM4E (0.41) | ATMKDM4EL3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL12333527 | 0.91 | KDM4E (0.34) | ATMKDM4EL3MBTL1HDAC4AVPR1A | |
| SCHEMBL2453123 | 0.91 | L3MBTL1 (0.44) | ATMKDM4EL3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL16865321 | 0.91 | L3MBTL1 (0.44) | ATMKDM4EL3MBTL1HDAC4ALDH1A1 | |
| SCHEMBL14296778 | 0.91 | HDAC4 (0.34) | ATMKDM4EL3MBTL1HDAC4FAAH | |
| SCHEMBL13557750 | 0.91 | KDM4E (0.41) | ATMKDM4EL3MBTL1HDAC4TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10008673-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | ATM 4337/4885KDM4E 2681/4885L3MBTL1 3745/4885 |
| US-10008673-B2 | Compounds for electronic devices | CYP1B1, CYP1A1, CYP2E1 | ATM 4337/4885KDM4E 2681/4885L3MBTL1 3745/4885 |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | ATM 4337/4885KDM4E 2681/4885L3MBTL1 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.