Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509085 | 0.74 | TDP1 (0.33) | — | |
| SCHEMBL14299081 | 0.70 | SIRT2 (0.43) | SIRT2 | |
| SCHEMBL3192661 | 0.68 | TSHR (0.42) | SIRT2ADH1CADH1AADH4 | |
| SCHEMBL3188358 | 0.68 | TSHR (0.42) | SIRT2ADH1CADH1AADH4 | |
| SCHEMBL3181124 | 0.68 | TSHR (0.42) | SIRT2ADH1CADH1AADH4 | |
| SCHEMBL3963526 | 0.68 | TSHR (0.42) | SIRT2ADH1CADH1AADH4 | |
| SCHEMBL28240077 | 0.67 | SIRT2 (0.37) | SIRT2 | |
| SCHEMBL3193317 | 0.66 | TSHR (0.39) | SIRT2ADH1CADH1AADH4 | |
| SCHEMBL22098433 | 0.65 | ALDH1A1 (0.32) | — | |
| SCHEMBL11845791 | 0.65 | SIRT2 (0.37) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045596-A1 | Ep2 Receptor Agonists | ASTERAND, INC. | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045596-A1 | Ep2 Receptor Agonists | PTGER2, PTGER1, PTGER3 | SIRT2 764/4885ADH1C 835/4885ADH1A 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.