Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.74 |
| ▸ | PRKCG | P05129 | 3/20 | 0.74 |
| ▸ | PRKCB | P05771 | 3/20 | 0.74 |
| ▸ | PRKCA | P17252 | 3/20 | 0.74 |
| ▸ | PRKCH | P24723 | 3/20 | 0.74 |
| ▸ | PRKCI | P41743 | 3/20 | 0.74 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.74 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.74 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.74 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.74 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 8/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1165362 | 0.85 | PRKD3 (1.00) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL30084457 | 0.85 | PRKD3 (1.00) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL28561537 | 0.85 | CYP3A4 (0.58) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL13672074 | 0.85 | MEN1 (0.57) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL13668459 | 0.85 | MEN1 (0.57) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL4270677 | 0.85 | MEN1 (0.57) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL20553518 | 0.84 | PRKD3 (0.98) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| Hydrochloric Acid SCHEMBL1321843 | 0.84 | PRKD3 (0.98) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL17303557 | 0.82 | CYP3A4 (0.57) | CYP3A4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL2960623 | 0.80 | MEN1 (0.71) | CYP3A4PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024284-A2 | SULFONYLATED PIPERAZINES AS CANNABINOID-1 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-02-28 | — | — | WO | disclosed |