SCHEMBL143

SCHEMBL143

c1ccc([C](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 5/20 0.53
CES2 O00748 4/20 0.53
TSHR P16473 2/20 0.53
ALDH1A1 P00352 2/20 0.53
DAO P14920 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
TDP1 Q9NUW8 5/20 0.47
CA2 P00918 3/20 0.47
CA4 P22748 3/20 0.47
CA12 O43570 3/20 0.47
CA1 P00915 3/20 0.47
CA9 Q16790 3/20 0.47
F2 P00734 2/20 0.47
CYP3A4 P08684 2/20 0.47
MAPT P10636 2/20 0.47
BLM P54132 2/20 0.47
CA3 P07451 2/20 0.47
CA14 Q9ULX7 2/20 0.47
HSD17B10 Q99714 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28911317 0.96 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
SCHEMBL29083294 0.96 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
Methane SCHEMBL29155195 0.96 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
SCHEMBL28839155 0.96 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
Charcoal, Activated SCHEMBL30423229 0.96 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
Bromide SCHEMBL28972076 0.96 CES1 (0.50) CES1CES2TSHRALDH1A1DAO
Boric Acid SCHEMBL29130048 0.89 CES1 (0.45) CES1CES2TSHRALDH1A1DAO
Potassium Bromide SCHEMBL21141912 0.89 CES1 (0.45) CES1CES2TSHRALDH1A1DAO
SCHEMBL28709940 0.87 CES1 (0.43) CES1CES2TSHRALDH1A1DAO
SCHEMBL4196341 0.84 CES2 (0.64) CES2ALDH1A1TDP1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 148473 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559514-B2 Synthesis of fluorinated nucleotides MERCK SHARP & DOHME LLC (US) 2026-02-24 US claimed
CN-119431697-A Method for continuous block polymerization of propylene and alpha-olefin 贝欧亿(山东)新材料有限公司 2025-02-14 CN claimed
CN-115485311-B Handle-bis (inden-2-yl) catalysts for producing vinylidene-terminated polyalphaolefins 埃克森美孚化学专利公司 2024-12-06 CN claimed
CN-119019586-A Ethylene-butadiene copolymer and single-kettle polymerization method thereof 正和集团股份有限公司 2024-11-26 CN claimed
CN-119019587-A Ethylene-butadiene copolymer and continuous production method thereof 正和集团股份有限公司 2024-11-26 CN claimed
US-12043641-B2 Minimally-invasive continuous clinical monitoring of small molecules with analytical accuracy TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2024-07-23 US claimed
US-12043642-B2 Process for the purification of oligonucleotides GENENTECH, INC. (US) 2024-07-23 US claimed
CN-118369094-A Process for preparing substituted pyrazolopyrimidines KSQ治疗公司 2024-07-19 CN claimed
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US claimed
EP-4039690-B1 A SUBSTANTIALLY DIASTEREOMERICALLY PURE PHOSPHORAMIDOCHLORIDATE, A METHOD AND A PHARMACEUTICAL COMPOSITION EISAI R&D MAN CO LTD (JP) 2024-07-17 EP claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed
US-3933800-A O-SUBSTITUTED OXIMES, MICROBIOCIDES GRUPPO LEPETIT S.P.A. (IT) 1976-01-20 US claimed
US-3933783-A Formation of peptide bonds in the presence of isonitriles AJINOMOTO CO., INC. (JA) 1976-01-20 US claimed
US-3933784-A Des-(ser13)-srif and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 US claimed
US-3933782-A (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 US claimed
US-3933870-A Synthesis of A-ring aromatic steroids HOFFMANN-LA ROCHE INC. (US) 1976-01-20 US claimed
US-3934008-A PEPTIDES, HYPOCALCAEMIC CIBA-GEIGY CORPORATION (US) 1976-01-20 US claimed
US-3932391-A Cephalosporin isocyanates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-13 US claimed
US-3932479-A BRONCHODILATOR, HYPOTENSIVE, ANTIULCER AMERICAN CYANAMID COMPANY (US) 1976-01-13 US claimed
US-3931140-A (H-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US claimed