Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18121772 | 0.85 | NPC1 (0.70) | KMT2ATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL1762394 | 0.83 | CYP11B1 (0.56) | KMT2ATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL4860249 | 0.82 | NPC1 (0.59) | CYP11B1CYP11B2CYP19A1NPC1TTR | |
| SCHEMBL14301290 | 0.82 | NPC1 (0.75) | KMT2ANPC1TTRACHE | |
| SCHEMBL4853290 | 0.80 | NPC1 (0.56) | CYP11B1CYP11B2CYP19A1NPC1TTR | |
| SCHEMBL4858306 | 0.79 | ACHE (0.52) | CYP11B1CYP11B2CYP19A1NPC1TTR | |
| SCHEMBL4861818 | 0.79 | NPC1 (0.55) | CYP11B1CYP11B2CYP19A1NPC1TTR | |
| SCHEMBL6906385 | 0.78 | CYP11B1 (0.62) | KMT2ATDP1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL5355534 | 0.78 | ACHE (0.51) | CYP11B1CYP11B2CYP19A1NPC1TTR | |
| SCHEMBL6906443 | 0.78 | CYP11B1 (0.60) | KMT2ATDP1CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022365-A2 | COMPOSITIONS FOR INFLUENCING THE EFFECTS OF ORGANOPHOSPHORUS COMPOUNDS AND USE OF GALANTHAMINE, ITS DERIVATIVES AND ANALOGUES FOR PRODUCING SUCH COMPOSITIONS | SANOCHEMIA LTD. (MT) | 2008-02-28 | — | — | WO | disclosed |