Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 4/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 8/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333039 | 0.81 | RET (0.45) | CACNA2D1 | |
| SCHEMBL14302002 | 0.78 | CCR4 (0.53) | CCR4TMEM97SIGMAR1 | |
| SCHEMBL14356890 | 0.78 | CCR4 (0.50) | CCR4TMEM97SIGMAR1 | |
| SCHEMBL13122757 | 0.73 | GSK3B (0.64) | — | |
| SCHEMBL23148336 | 0.72 | NTRK1 (0.43) | — | |
| SCHEMBL23148335 | 0.72 | NTRK1 (0.43) | — | |
| SCHEMBL4333275 | 0.72 | AXL (0.33) | — | |
| SCHEMBL15393779 | 0.72 | GSK3B (0.44) | CCR4TMEM97SIGMAR1 | |
| SCHEMBL1440944 | 0.72 | CDK2 (0.39) | — | |
| SCHEMBL1442100 | 0.72 | PIM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873157-A1 | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-01-02 | — | — | EP | disclosed |
| WO-2007147647-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME. | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |