SCHEMBL14302425

SCHEMBL14302425

Nc1ccc(-c2cccc(-c3cccc(-c4ccc(N)cc4)c3)c2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.70
CYP3A4 P08684 4/20 0.68
TDP1 Q9NUW8 2/20 0.68
HSD17B10 Q99714 2/20 0.68
ALDH1A1 P00352 3/20 0.65
TP53 P04637 1/20 0.65
MAOA P21397 1/20 0.59
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
ESR1 P03372 1/20 0.55
CA12 O43570 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
CA1 P00915 1/20 0.48
APP P05067 2/20 0.48
CYP2C9 P11712 1/20 0.48
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48
MAPT P10636 3/20 0.47
HPGD P15428 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14309787 1.00 TAAR1 (0.70) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL309757 1.00 TAAR1 (0.70) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL14565868 0.95 TAAR1 (0.79) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL15468609 0.95 TAAR1 (0.79) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL18960514 0.92 MAOA (0.73) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL14396439 0.91 TAAR1 (0.81) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL31097208 0.90 MAOA (0.70) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
Benzidine SCHEMBL29236355 0.89 MAOA (0.76) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL31264296 0.89 MAOA (0.76) TAAR1CYP3A4TDP1HSD17B10ALDH1A1
SCHEMBL29350106 0.89 MAOA (0.76) TAAR1CYP3A4TDP1HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1880990-A1 NOVEL ORGANIC ELECTROLUMINESCENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME, AND THIN-FILM-FORMING SOLUTION FOR ORGANIC ELECTROLUMINESCENCE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-23 EP disclosed