Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29888385 | 0.87 | CCR2 (0.60) | CCR2CYP2C9TSHR | |
| SCHEMBL306504 | 0.87 | CCR2 (0.60) | CCR2CYP2C9TSHR | |
| SCHEMBL18714270 | 0.87 | CCR2 (0.63) | CCR2CYP2C9TSHR | |
| SCHEMBL306214 | 0.87 | CCR2 (0.60) | CCR2CYP2C9TSHR | |
| SCHEMBL304956 | 0.85 | CCR2 (0.57) | CCR2CYP2C9TSHR | |
| SCHEMBL305899 | 0.84 | CYP2C9 (0.66) | CCR2CYP2C9TSHR | |
| SCHEMBL1957811 | 0.84 | CCR2 (0.60) | CCR2CYP2C9TSHR | |
| SCHEMBL126997 | 0.84 | CYP2C9 (0.66) | CCR2CYP2C9TSHR | |
| SCHEMBL315470 | 0.84 | CYP2C9 (0.69) | CCR2CYP2C9 | |
| SCHEMBL14303599 | 0.82 | CYP2C9 (0.64) | CCR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008431-A2 | HETEROARYL SULFONAMIDES AND CCR2/CCR9 | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |