Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680716 | 0.83 | NPSR1 (0.65) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL1264434 | 0.82 | CYP1B1 (0.49) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL22258208 | 0.81 | KDM4E (0.70) | CYP1B1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL14303158 | 0.81 | CA12 (0.55) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL14303136 | 0.80 | CASP3 (0.58) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL14303135 | 0.80 | CA12 (0.54) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL14309282 | 0.80 | CA12 (0.54) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL1263256 | 0.80 | CYP1B1 (0.50) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL1270493 | 0.80 | CHRM5 (0.52) | CYP1B1CA12CA1CA2CA9 | |
| SCHEMBL6165776 | 0.79 | CASP3 (0.62) | CYP1B1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977754-B1 | WRITABLE AND ERASABLE HIGH-DENSITY OPTICAL STORAGE MEDIA | CIBA SC HOLDING AG (CH) | 2008-01-16 | — | — | EP | disclosed |