Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13146441 | 0.87 | CCR2 (0.54) | CCR2 | |
| SCHEMBL13146698 | 0.86 | CCR2 (0.53) | CCR2 | |
| SCHEMBL3095653 | 0.85 | CCR2 (0.55) | CCR2 | |
| SCHEMBL13146439 | 0.85 | CCR2 (0.52) | CCR2 | |
| SCHEMBL3095535 | 0.84 | CCR2 (0.56) | CCR2 | |
| SCHEMBL3078340 | 0.82 | CCR2 (0.61) | CCR2 | |
| SCHEMBL3095664 | 0.82 | CCR2 (0.60) | CCR2 | |
| SCHEMBL3091669 | 0.78 | CCR2 (0.56) | CCR2 | |
| SCHEMBL3095504 | 0.78 | CCR2 (0.55) | CCR2 | |
| SCHEMBL1104715 | 0.77 | CCR2 (0.67) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |