Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.65 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.45 |
| ▸ | MTOR | P42345 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.42 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766389 | 0.84 | NOS1 (0.64) | NOS1NUDT1PIK3CAMTORPIK3CD | |
| SCHEMBL14302977 | 0.84 | NOS1 (0.64) | NOS1NUDT1PIK3CAMTORPIK3CD | |
| SCHEMBL3755512 | 0.81 | NOS1 (0.67) | NOS1NUDT1CRHBPCRHR2PIK3CA | |
| SCHEMBL3768171 | 0.81 | NOS1 (0.67) | NOS1NUDT1CRHBPCRHR2PIK3CA | |
| SCHEMBL3765592 | 0.81 | NOS1 (0.64) | NOS1NUDT1CRHBPCRHR2PIK3CA | |
| SCHEMBL3763715 | 0.81 | NOS1 (0.78) | NOS1PIK3CAMTORPIK3CDPIK3CG | |
| SCHEMBL3765089 | 0.81 | NOS1 (0.59) | NOS1NUDT1CRHBPCRHR2PIK3CA | |
| SCHEMBL3755666 | 0.81 | NOS1 (0.69) | NOS1NUDT1CRHBPCRHR2PIK3CA | |
| SCHEMBL3759363 | 0.81 | NOS1 (0.72) | NOS1NUDT1PIK3CAMTORPIK3CD | |
| SCHEMBL3759341 | 0.81 | NOS1 (0.65) | NOS1NUDT1CRHBPCRHR2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009079-A2 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |